Many saw the events as an opportunity to shake up the "old society" and traditional morality, focusing especially on the education system and employment.[citation needed] It began as a long series of student strikes that broke out at a number of universities and lycées in Paris, following confrontations with university administrators and the police. The de Gaulle administration's attempts to quell those strikes by police action only inflamed the situation further, leading to street battles with the police in the Latin Quarter, followed by a general strike by students and strikes throughout France by eleven million French workers, roughly two-thirds of the French workforce. The protests reached such a point that de Gaulle created a military operations headquarters to deal with the unrest, dissolved the National Assembly and called for new parliamentary elections for 23 June 1968.

The government was close to collapse at that point (de Gaulle had even taken temporary refuge at an air force base in Germany), but violence evaporated almost as quickly as it arose. Workers went back to their jobs, after a series of deceptions by the Confédération Générale du Travail (the leftist union federation) and the PCF. When the elections were finally held in June, the Gaullist party emerged even stronger than before.

May 1968 was a political failure for the protesters, but it had an enormous social impact. In France, it is considered to be the watershed moment when a conservative moral ideal (religion, patriotism, respect for authority) shifted towards a more liberal moral ideal (equality, sexual liberation, human rights) that today better describes French society, in theory if not in practice.[citation needed] Although this change did not take place solely in this one month, the term mai 68 is used to refer to this general shift in principles, especially when referring to its most idealistic aspects.

On 22 March far-left groups, a small number of prominent poets and musicians, and 150 students, occupied an administration building at Paris University at Nanterre and held a meeting in the university council room dealing with class discrimination in French society and the political bureaucracy that controlled the school's funding.

The school's administration called the police, who surrounded the university. After the publication of their wishes, the students left the building without any trouble. After this first record, some leaders of what was named the "Movement of 22 March" were called together by the disciplinary committee of the university.

Following months of conflicts between students and authorities at the University of Paris at Nanterre, the administration shut down that university on 2 May 1968. Students at the Sorbonne University in Paris met on 3 May to protest against the closure and the threatened expulsion of several students at Nanterre. On Monday, 6 May, the national student union, the Union Nationale des Étudiants de France (UNEF) — still the largest student union in France today — and the union of university teachers called a march to protest against the police invasion of Sorbonne. More than 20,000 students, teachers and supporters marched towards the Sorbonne, still sealed off by the police, who charged, wielding their batons, as soon as the marchers approached. While the crowd dispersed, some began to create barricades out of whatever was at hand, while others threw paving stones, forcing the police to retreat for a time. The police then responded with tear gas and charged the crowd again. Hundreds more students were arrested.

High school student unions spoke in support of the riots on 6 May. The next day, they joined the students, teachers and increasing numbers of young workers who gathered at the Arc de Triomphe to demand that:

Negotiations broke down, and students returned to their campuses after a false report that the government had agreed to reopen them, only to discover the police still occupying the schools. The students now had a near revolutionary fervor.

On Friday, 10 May, another huge crowd congregated on the Rive Gauche. When the riot police again blocked them from crossing the river, the crowd again threw up barricades, which the police then attacked at 2:15 in the morning after negotiations once again foundered. The confrontation, which produced hundreds of arrests and injuries, lasted until dawn of the following day. The events were broadcast on radio as they occurred and the aftermath was shown on television the following day. Allegations were made that the police had participated, through agents provocateurs, in the riots, by burning cars and throwing Molotov cocktails .

The government's heavy-handed reaction brought on a wave of sympathy for the strikers. Many of the nation's more mainstream singers and poets joined after the heavy-handed police brutality came to light. American artists also began voicing support of the strikers. The PCF reluctantly supported the students, whom it regarded as adventurers and anarchists, and the major left union federations, the Confédération Générale du Travail (CGT) and the Force Ouvrière (CGT-FO), called a one-day general strike and demonstration for Monday, 13 May.